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The Journal of Basic and Applied Zoology

Table 3 Influence of GABA (200 mg/Kg b.wt; 3 weeks) on oxidant biomarkers values in jejunum of 6 Gy whole body gamma-irradiated rats

From: Gamma-aminobutyric acid ameliorates gamma rays-induced oxidative stress in the small intestine of rats

Parameter

AOPP

(μmol/L)

MDA

(nmol/g)

Groups

Control

164.90 ± 6.59

112.50 ± 7.65

GABA

P1

158 ± 5.19

(−8%)

NS

103.80 ± 11.63

(−8%)

<0.05

IR

P1

285.80 ± 6.76

(73%)

<0.001

158.70 ± 6.75

(46%)

<0.001

IR + GABA

P1

P2

248.20 ± 19.97

(51%)

<0.001

<0.001

116.70 ± 11.88

(4%)

NS

<0.001

  1. Values are expressed as Means ± Standard Deviation (n = 10). Values between brackets show a percentage of change from Control. P1: significance vs control. P2: significance vs respective group (IR) not receiving GABA. NS: non-significant. P < 0.001 highly significant
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