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Table 3 Changes in the level of serum liver biochemical markers; transaminase activity (AST and ALT) and alkaline phosphatase activity (ALP) of male Swiss albino mice treated with PBS, vitamin C (1136 μM/kg), CMZ (46 μM/kg), or a combination of CMZ and vitamin C with the same dose of each intraperitoneally (i.p.) daily over 4 weeks

From: Immunobiochemical modulations caused by clomazone in Swiss albino mice

Experimental groups

ALT (U/l)

AST (U/l)

ALP (U/l)

PBS

60.6 ± 4.04

91.0 ± 5.80

167.20 ± 6.73

Vitamin C

62.4 ± 4.58

94.0 ± 6.24

172.20 ± 4.91

CMZ

82.0 ± 2.86*$

120.0 ± 2.00*$

201.40 ± 4.10*$

CMZ/vitamin C

73.0 ± 3.72*#

106.2 ± 3.99#

179.80 ± 4.94#

  1. Data were represented as mean ± SE (n = 5)
  2. PBS phosphate buffer saline, CMZ clomazone
  3. *Statistically significant vs. PBS-treated group; $statistically significant vs. vitamin C-treated group; #statistically significant vs. CMZ-treated group. P ≤ 0.05