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Fig. 15 | The Journal of Basic and Applied Zoology

Fig. 15

From: A mechanism underlying the neurotoxicity induced by sodium fluoride and its reversal by epigallocatechin gallate in the rat hippocampus: involvement of NrF2/Keap-1 signaling pathway

Fig. 15

Effect of EGCG on the Fl-induced changes in the histology of neurons in the hippocampus of control and Fl exposure (ad). a Control rats: normal hippocampal tissue histology is seen (× 40). b EGCG rats: although similar hippocampal tissue histology was observed compared to control (× 40). c Fl-treated rats: increased degenerative changes, shrinkage cytoplasm, and extensively dark picnotic nuclei in neurons of the hippocampus are seen (× 40). d Fl-treated rats with EGCG: effective preventing of degenerative changes and shrunken in cytoplasm and nuclei are prominent in neuronal cells. (H&E × 40)

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