The protective effect of N-acetyl cysteine against carbon tetrachloride toxicity in rats

The Journal of Basic and Applied Zoology

Table 2 Percentages of abnormal sperms and tail moments in rats post-treatment with CCL₄ and/or NAC

Treatment	No of counted sperms	Types of sperm head abnormalities								Tail abnormalities	Total			Tail moment%
Treatment	No of counted sperms	t	col	d-o	b-s	wh	am	ac	dh	Tail abnormalities	Total	%	S.D.	Mean	S.D.
Control	5000/group	–	–	–	2	18	4	4	0	8	36	0.72	2.28	0.1505	0.036
CCL₄		12	–	14	–	31	68	5	3	6	139	2.78	6.02^d	1.642	0.976^b
NAC		10	–	9	7	8	5	4	4	7	54	1.08	5.3 ^a	0.3939	0.336^a
CCL4 + NAC		9	5	15	–	6	11	3	–	8	57	1.14	4.34^af	0.3036	0.265^ae
NAC then CCL4		12	6	6	3	16	13	5	1	7	69	1.38	6.14^af	0.2474	0.04^ce

4 animals were used for comet assay
t triangular, col collapsed, am amourphous, bs banana shape, wh without hook, do deformed orientation, ac acute curvature, dh double head, S.D. standard deviation
^aP > 0.05 compared with control
^bP < 0.05 compared with control
^cP < 0.01 compared with control
^dP < 0.0001 compared with control
^eP < 0.05 compared with CCL4
^fP < 0.01compared with CCL4