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Table 1 Cellular alternation in peripheral blood leucocytes profile of mice treated with Diclo, Ibu, and Para daily for 1 month

From: Adverse effects induced by diclofenac, ibuprofen, and paracetamol toxicity on immunological and biochemical parameters in Swiss albino mice

Treatments WBC count (× 103) Leucocytes relative%
Lymphocytes Monocytes Neutrophils Basophils
Control 5.53 ± 0.70 79.80 ± 4.40 3.49 ± 0.54 12.81 ± 0.46 1.95 ± 0.24
Diclo (7.4 mg/kg) 7.80 ± 0.60 77.9 ± 2.57 6.17 ± 0.38 8.66 ± 0.42*** 7.23 ± 1.01***
Diclo (14 mg/kg) 8.07 ± 1.10 77.63 ± 0.20 5.93 ± 0.44 12.72 ± 1.38 3.89 ± 0.44
Ibu (60 mg/kg) 6.90 ± 0.40 78.10 ± 7.11 13.00 ± 0.81*** 10.24 ± 0.08 3.69 ± 0.71
Ibu (120 mg/kg) 7.10 ± 0.68 75.80 ± 3.26 4.87 ± 0.10 8.30 ± 0.65*** 2.89 ± 0.21
Para (36.7 mg/kg) 6.60 ± 0.91 80.46 ± 7.50 7.11 ± 2.23 11.30 ± 0.46 3.52 ± 0.23
Para (73.4 mg/kg) 8.03 ± 1.11 75.22 ± 2.79 9.73 ± 1.17*** 10.91 ± 0.29 4.70 ± 0.16*
  1. Data were represented as mean ± SE (n = 3)
  2. *Statistically significant comparison of control group and other treated groups (p < 0.05), ***highly significant (p < 0.01)