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Table 1 Cellular alternation in peripheral blood leucocytes profile of mice treated with Diclo, Ibu, and Para daily for 1 month

From: Adverse effects induced by diclofenac, ibuprofen, and paracetamol toxicity on immunological and biochemical parameters in Swiss albino mice

Treatments

WBC count (× 103)

Leucocytes relative%

Lymphocytes

Monocytes

Neutrophils

Basophils

Control

5.53 ± 0.70

79.80 ± 4.40

3.49 ± 0.54

12.81 ± 0.46

1.95 ± 0.24

Diclo (7.4 mg/kg)

7.80 ± 0.60

77.9 ± 2.57

6.17 ± 0.38

8.66 ± 0.42***

7.23 ± 1.01***

Diclo (14 mg/kg)

8.07 ± 1.10

77.63 ± 0.20

5.93 ± 0.44

12.72 ± 1.38

3.89 ± 0.44

Ibu (60 mg/kg)

6.90 ± 0.40

78.10 ± 7.11

13.00 ± 0.81***

10.24 ± 0.08

3.69 ± 0.71

Ibu (120 mg/kg)

7.10 ± 0.68

75.80 ± 3.26

4.87 ± 0.10

8.30 ± 0.65***

2.89 ± 0.21

Para (36.7 mg/kg)

6.60 ± 0.91

80.46 ± 7.50

7.11 ± 2.23

11.30 ± 0.46

3.52 ± 0.23

Para (73.4 mg/kg)

8.03 ± 1.11

75.22 ± 2.79

9.73 ± 1.17***

10.91 ± 0.29

4.70 ± 0.16*

  1. Data were represented as mean ± SE (n = 3)
  2. *Statistically significant comparison of control group and other treated groups (p < 0.05), ***highly significant (p < 0.01)