Fig. 2From: Toxicological studies on commercial hair dye brand commonly used in Saudi Arabia: histological study of the liver, kidney, heart, and testisSections in the rat liver central vein region (CV) show the following: G1: CO (control) group with normal hepatocyte cell cords (black arrows) and thin intervening sinusoids (white arrows) (H-E, × 200). G2: LD dye (low dose) showing mild granularity of hepatocytes and nuclei with dark stained dense chromatin (black arrows), sinusoidal congestion (white arrows), and focal hemorrhage (star). Central vein (CV) showed endothelial lining damage (dotted arrow) (H-E, × 200). G3: HD dye (high dose) with marked central vein (CV) congestion and vacuolar degeneration of nearby hepatocytes (arrows), swollen sinusoids that could not be seen. Others on the right are darkly stained shrunken and degenerated (dotted arrows) (H-E, × 200)Back to article page