Evaluation of hepcidin level in chronic hepatitis C Egyptian patients undergoing regular hemodialysis

The Journal of Basic and Applied Zoology

Table 2 Hepcidin and iron status markers of the investigated groups

	Control group N = 20	HD patients N = 80	P	HCV – ve HD N = 40	HCV + ve HD N = 40	P
Hepcidin
Hepcidin “ng/ml”	338.92 ± 88.56	583.25 ± 353.83	P < 0.01	570.64 ± 59.38	595.86 ± 52.96	NS
Iron parameters
Hemoglobin “g/dl”	12.01 ± 1.69	9.09 ± 1.85	P < 0.001	8.36 ± 0.29	9.81 ± 0.24	P < 0.001
Hematocrit “%”	34.47 ± 4.17	27.08 ± 6.96	P < 0.001	25.61 ± 1.31	28.54 ± 0.78	P < 0.001
MCV “fl”	78.15 ± 6.14	85.52 ± 7.23	P < 0.001	83.94 ± 1.09	87.08 ± 1.15	P < 0.001
MCH “pg”	27.16 ± 2.89	29.17 ± 2.94	P < 0.01	28.38 ± 0.44	29.96 ± 0.45	P < 0.01
MCHC “g/dl”	34.73 ± 1.20	37.95 ± 33.60	NS	33.91 ± 0.30	41.98 ± 7.50	NS
Ferritin “ng/ml”	176.35 ± 55.91	637.69 ± 591.11	P < 0.01	276.77 ± 53.66	998.62 ± 90.19	P < 0.01
Iron “μg/dl”	84.20 ± 29.85	249.86 ± 209.24	P < 0.001	108.07 ± 11.57	391.65 ± 32.43	P < 0.001
Erythropoietin dos “IU/week”	0	4648 ± 1484.8	–	4480 ± 200	4800 ± 240	NS

All data are presented as mean ± SD, N number of cases, HD haemodialysis, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, RBCs red blood cells count, NS non-significant