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Table 3 Correlation between hepcidin and iron status markers with clinical profile in hemodialysis HCV seropositive and seronegative patient

From: Evaluation of hepcidin level in chronic hepatitis C Egyptian patients undergoing regular hemodialysis

Clinical profile

HCV + ve HD

HCV – ve HD

Iron

Ferritin

Hepcidin

Iron

Ferritin

Hepcidin

R

P value

R

P value

R

P value

r

P value

r

P value

r

P value

Erythropoietin dose

− 0.501**

P < 0.01

0.406**

P < 0.01

0.249

NS

0.023

NS

0.272

NS

0.121

NS

ALT

0.359*

P < 0.05

0.394*

P < 0.05

− 0.051

NS

0.226

NS

0.372*

P < 0.05

− 0.071

NS

AST

0.128

NS

0.161

NS

− 0.063

NS

0.358*

P < 0.05

0.523**

P < 0.05

− 0.005

NS

Urea

0.112

NS

− 0.005

NS

− 0.196

NS

− 0.086

NS

0.128

NS

0.029

NS

Creatinine

− 0.127

NS

− 0.261

NS

− 0.079

NS

− 0.214

NS

0.062

NS

0.110

NS

Total bilirubin

0.002

NS

0.061

NS

0.034

NS

− 0.190

NS

− 0.129

NS

− 0.159

NS

ALP

0.035

NS

− 0.027

NS

− 0.104

NS

− 0.205

NS

− 0.161

NS

− 0.067

NS

Albumin

− 0.140

NS

0.054

NS

− 0.011

NS

− 0.069

NS

− 0.070

NS

0.324

NS

Potassium

0.100

NS

0.044

NS

− 0.086

NS

− 0.026

NS

0.066

NS

0.066

NS

Sodium

− 0.247

NS

− 0.177

NS

− 0.046

NS

− 0.167

NS

− 0.223

NS

0.081

NS

Iron

1.000

NS

0.784**

P < 0.01

− 0.22

NS

1.000

NS

0.715**

P < 0.01

0.031

NS

Ferritin

0.784**

P < 0.01

1.000

NS

− 0.145

NS

0.715**

P < 0.01

1.000

NS

0.071

NS

Hemoglobin

0.198

NS

0.374*

P < 0.05

− 0.105

NS

− 0.139

NS

0.081

NS

0.168

NS

Hepcidin

− 0.122

NS

− 0.145

NS

1.000

NS

0.031

NS

0.071

NS

1.000

NS

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, NS non-significant
  2. * = P < 0.05, **= P < 0.01
  3. Data in bold are significant