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Fig. 6 | The Journal of Basic and Applied Zoology

Fig. 6

From: Ameliorative effect of bee venom and its extracted bradykinin-potentiating factor on neurological alteration induced by acrylamide and chips administration

Fig. 6

Photomicrographs of the cerebellar region showing the gray (GM) and white matter (WM), granular cell layer (GCl), Purkinje cell layer (PCL), and the molecular cell layer (MCl) of control are shown (A, A1). In the acrylamide-administrated groups, degeneration of the Purkinje cell was shown at 60 days (arrows, D) compared to 30 and 45 days (arrows; B, C) and the control (A1). In the chips feeding groups, Purkinje cell degeneration was noted at 60 (arrows, G) than at 30 (E) and 45 (arrows, F) days of feeding. The BV- (H) and BPF-treated groups at 60 days of treatment (I) showed Purkinje cells similar to the control. The acrylamide-administrated groups treated with either BV (J) or BPF (K) showed improvement compared to degeneration which has been detected in the acrylamide group. The chips feeding groups treated with either BV (L) or BPF (M) showed improvement in Purkinje cell integrity compared to chips-induced Purkinje cell degeneration. H&E stain; scale bar, A 50 μm; A1–M 10 μm

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