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Table 4 Effect of BV and BPF treatment on acrylamide and chips administration on the plasma creatinine (mg/dl), urea (mg/dl), and uric acid (mg/dl) of mice for 60 days

From: Counter effect of bee venom and its extracted bradykinin-potentiating factor on acrylamide and chips administration-induced complications in the liver and kidney of male mice

  Cont. Acr. Chip. BV BPF Acr + BV Acr + BPF Chip + BV Chip + BPF
Creatinine
Mean ± SE
0.842 ± 0.04 4.036 ± 0.25a** 2.69 ± 0.344a, b** 0.79 ± 0.08b, c** 0.86 ± 0.041b, c** 1.21 ± 0.12b, c** 1.062 ± 0.102b, c** 1.226 ± 0.17b, c** 1.05 ± 0.141b, c**
% of change (1)   + 379.33 + 219.47 − 6.17 + 2.13 + 33.01 + 26.12 + 45.60 + 24.70
(2)    − 33.35 − 80.46 − 78.69 − 70.62 − 73.68 −69.77 − 73.98
(3)     − 70.63 − 68.03 − 55.02 − 60.59 − 54.42 − 60.96
Urea
Mean ± SE
29.46 ± 2.61 57.36 ± 6.85a** 46.1 ± 3.71a, b** 29.74 ± 1.42b, c** 29.42 ± 2.35b, c** 26.92 ± 1.83b, c** 28.66 ± 2.98b, c** 35.34 ± 2.22b**, c* 33.68 ± 1.63b**, c*
% of change (1)   + 94.70 + 56.48 + 0.95 − 0.13 − 8.62 − 2.71 + 30.14 + 14.32
(2)    −19.63 − 48.15 − 48.71 − 53.06 − 50.03 − 38.39 − 41.28
(3)     − 35.49 − 33.97 − 41.60 − 37.83 − 23.34 − 26.94
Uric acid
Mean ± SE
5 ± 0.71 19.8 ± 2.22a** 17.8 ± 1.93a** 4.8 ± 0.8b, c** 5.2 ± 0.58b, c** 4.8 ± 0.73b, c** 5.8 ± 0.73b, c** 8.2 ± 1.067a*, b, c** 8.6 ± 1.029a, c*, b**
% Of Chang (1)   + 296 + 256 − 4 + 4 − 4 + 16 + 64 + 72
(2)    − 10.10 − 75.75 − 73.73 − 75.75 − 70.70 − 58.58 − 56.56
(3)     − 73.03 − 70.78 − 73.03 −67.41 − 53.93 − 51.68
  1. Significance difference between control and treated groups. n = 5. % of change: (1) from control, (2) from acrylamide, (3) from chips
  2. *P < 0.05 significant, **P < 0.001 highly significant
  3. aSignificance difference to control
  4. bSignificance difference to acrylamide
  5. cSignificance difference to chips