Fig. 3
From: The ameliorative impacts of curcumin on copper oxychloride-induced hepatotoxicity in rats
a A section in the liver of control rats showing normal distribution of collagen fibers and fibrils, normal hepatocytes, normal blood sinusoids, and portal area. b A section in the liver of treated rats with curcumin extract showing normal distribution of collagen fibers. c, d A section in the liver of 500 and 2000 mg/kg COC-treated rat showing degenerated hepatocytes with deposition of collagen fibers around the central vein and in the dilated blood sinusoids. e A section in the liver of 2000 mg/kg COC- and curcumin-treated rat showing branches of the hepatic portal vein, hepatic artery, and bile duct with marked deposition of collagen fibers surrounding them. f A section in the liver of 500 mg/kg COC- and curcumin-treated rat showing branches of the hepatic portal vein, hepatic artery, and bile duct with mild deposition of collagen fibers surrounding them (Masson’s trichrome × 400)