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Table 4 The effect of soybean oil (SBO), Triton WR-1339, and their combination on plasma, liver, and brain biochemical parameters in male rats compared to a control group

From: Triton WR-1339-induced hyperlipidemia, DNA fragmentation, neurotransmitters inhibition, oxidative damage, histopathological and morphometric changes: the protective role of soybean oil

Parameters

Experimental groups

Control

Triton

Triton + SBO

Plasma

 AST

34.8 ± 1.34

65.8 ± 2.09a

45.5 ± 1.42ab

 ALT

29.8 ± 0.98

59.1 ± 1.56a

39.9 ± 1.23ab

 ACP

8.32 ± 0.43

16.89 ± 0.64a

11.12 ± 0.53ab

 ALP

39.8 ± 1.76

73.9 ± 1.43a

51.8 ± 1.65ab

 LDH

985 ± 10.80

1789 ± 15.9a

1298 ± 20.9ab

 MAO

30.1 ± 1.10

19.9 ± 1.021a

25.1 ± 2.23b

 AChE*

2.98 ± 0.12

2.32 ± 0.09a

2.64 ± 0.11b

 T.P

7.8 ± 0.34

4.5 ± 0.35a

5.8 ± 0.252ab

 Albumin

4.9 ± 0.12

2.9 ± 0.11a

3.9 ± 0.13ab

 Globulin

2.9 ± 0.12

1.6 ± 0.08a

1.9 ± 0.20ab

 Urea

36.9 ± 1.26

50.1 ± 1.23a

41.2 ± 1.53ab

 Creatinine

0.95 ± 0.05

1.69 ± 0.06a

1.29 ± 0.07ab

 Bilirubin

1.52 ± 0.06

2.82 ± 0.07a

1.79 ± 0.04ab

Liver

 AST

99.1 ± 3.11

50.9 ± 2.98a

82.9 ± 3.27ab

 ALT

69.9 ± 2.98

42.1 ± 2.12a

58.7 ± 2.32ab

 ALP

223 ± 11.2

131 ± 7.1a

186 ± 9.90ab

 ACP

21.5 ± 0.98

9.9 ± 0.56a

16.8 ± 0.78ab

 LDH

1760 ± 54

1279 ± 43 a

1589 ± 39ab

 P.C

125 ± 4.1o

87 ± 2.3a

108 ± 3.81ab

Brain

 AChE**

14.97 ± 0.52

10.78 ± 0.41a

12.91 ± 0.210ab

 LDH

1210 ± 35

760±29a

989 ± 23ab

 MAO

6.99 ± 0.23

3.21 ± 0.13a

4.89 ± 0.09b

 P.C

89 ± 2.34

68 ± 3.21a

78 ± 1.99b

  1. Values are expressed as means ± SE
  2. AST aspartate transaminases (U/L), liver AST (U/mg protein), ALT alanine transaminases (U/L), liver ALT(U/mg protein), ACP acid phosphatase (U/L), liver ACP (U/mg protein), ALP alkaline phosphatase (U/L) liver ALP (U/mg protein), LDH lactate dehydrogenase (1 U/L), liver and brain LDH (IU/g), T.P total protein (mg/dl), *Plasma AChE acetylcholinesterase (μmole substrate hydrolyzed/μl plasma/min), **Brain AChE μmole substrate hydrolyzed/mg protein/min, MAO monoamine oxidase (U/g), P.C. protein content (mg/g tissue), albumin (g/dl), globulin (g/dl), urea (mg/dl), creatinine (mg/dl), bilirubin (mg/dl)
  3. aThe mean values are significantly different compared to a control group at P < 0.05
  4. bThe mean values are significantly different compared to triton-intoxicated group at P < 0.05