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Table 5 Effect of prolonged exposure to LC25 of Mefloquine drug for 2 weeks on some glycolytic enzymes in soft tissues of Lymnaea natalensis snails

From: Effect of mefloquine on biological and biochemical aspects of Lymnaea natalensis snails infected with Fasciola gigantica

Parameters treatment

Control

Mean ± SD

Mefloquine drug

Mean ± SD

%

Hexokinase (HK)

5.4 ± 0.22

3.6 ± 0.44***

33%

Pyruvate kinase(PK)

1.8 ± 1.4

1.2 ± 0.8***

33%

phosphofructokinase (PFK)

3.4 ± 2.8

1.4 ± 1.5***

58.8%

Lactate dehydrogenase(LHD)

7.4 ± 2.4

5.3 ± 1.4***

28.38%

Glucose phosphate isomerase (GPI)

2.56 ± 0.56

1.12 ± 0.33***

−56.25

  1. *p < 0.05; **p < 0.01; ***p < 0.001. Enzyme activity μmol/min/mg protein