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Table 2 Comparison of physical and biochemical parameters between PWS and OC subjects

From: Excessive carbohydrate consumption and body mass index: the risk factors for type 2 diabetes mellitus in patients with Prader-Willi syndrome in Tamil Nadu population

Characteristic

PWS

OC

Total

p value

Male

Female

Male

Female

PWS

OC

Adolescent, 12–19 years

N

9

4

7

5

13

12

 

 Age (years)

15.5 ± 2.0

15.2 ± 3.3

16.2 ± 2.4

14.8 ± 3.0

15.4 ± 2.3

15 ± 2.5

0.6807

 Height (cm)

109.3 ± 2.4

107.5 ± 3.6

130 ± 5.0

129 ± 5.8

108.7 ± 2.8**

129.5 ± 5.1

< 0.0001

 Weight (kg)

62.4 ± 7.3

59.5 ± 7.1

43.7 ± 5.9

44 ± 5.1

61.5 ± 7.1**

46.4 ± 6.7

< 0.0001

 BMI (kg/m2)

52.1 ± 5.0

51.3 ± 3.7

27.6 ± 2.9

27.0 ± 2.2

51.9 ± 4.5**

27.4 ± 2.5

< 0.0001

 Cholesterol (mg/dl)

233.5 ± 13.4

220.5 ± 8.3

213.2 ± 18.6

205.8 ± 29.0

229.5 ± 13.3*

210.1 ± 22.6

0.0146

 Glucose

3.3 ± 1.4

4 ± 0.8

3 ± 1.4

1 ± 1.4

3 ± 1.0

2.6 ± 1.1

0.5482

 Fasting blood sugar

200.5 ± 16.1

208 ± 7.9

131.4 ± 46.5

115.8 ± 48.0

202.8 ± 14.2**

124.9 ± 45.6

< 0.0001

 Postprandial blood sugar

287.5 ± 52.7

317 ± 31.8

200.1 ± 77.2

211 ± 66.61

296.6 ± 48.0**

204.6 ± 70.0

0.0008

Adult, 20–28 years

N

7

3

6

5

10

11

 

 Age (years)

25.8 ± 2.1

23.3 ± 3.2

23.5 ± 3.0

24.6 ± 1.6

25.1 ± 2.6

24 ± 2.4

0.3279

 Height (cm)

120 ± 5.41

119.6 ± 8.3

139.5 ± 11.3

143.8 ± 7.0

119.9 ± 4.6**

141.4 ± 9.4

< 0.0001

 Weight (kg)

88.8 ± 7.1

82.3 ± 0.5

55.3 ± 7.2

62.6 ± 6.6

86.9 ± 6.6**

63.4 ± 8.3

< 0.0001

 BMI (kg/m2)

61.7 ± 4.5

57.5 ± 2.9

28.5 ± 3.3

31.8 ± 2.8

60.5 ± 4.4**

31.6 ± 3.3

< 0.0001

 Cholesterol (mg/dl)

238.2 ± 10.0

243.3 ± 17.0

210.6 ± 12.5

223 ± 21.3

239.8 ± 11.7*

216.2 ± 17.3

0.0018

 Glucose

3.57 ± 1.6

3 ± 1.7

3 ± 0.1

3.5 ± 0.7

2.6 ± 1.3

3.2 ± 0.5

0.1711

 Fasting blood sugar

199.2 ± 16.8

200 ± 7

128.5 ± 61.0

142 ± 60.3

199.5 ± 14.1*

134.6 ± 58.0

0.0027

 Postprandial blood sugar

307.5 ± 52.1

280 ± 31.5

225.8 ± 57.3

243.8 ± 73.4

299.3 ± 47.0

234 ± 62.4

0.0146

  1. The physical and biochemical parameters were calculated by using mean (SD) in both subjects, and all data are reported in Additional file 1: Table S1a and b. PWS, Prader-Willi syndrome, OC obesity control, BMI body mass index, SD, standard deviation. **p values are extremely significant, *p values are highly significant; p values are significant