Table 2 The levels of malondialdehyde (MDA) and glutathione (GSH), after 1, 7, and 14 days in the brain, liver, and kidneys of control rats (I), and those administered 0.5 g and 1.0 g of NiO-NPs (II and III), 0.5 g and 1.0 g of Co₃O₄-NPs (IV and V,) as well as mixtures of NiO-NPs + Co₃O₄-NPs (0.25 g + 0.25 g, VI) and (0.5 g + 0.5 g, VII) per kilogram body weight, respectively

1

5.11 ± 0.19^a

6.54 ± 0.04^c

7.31 ± 0.31^d

7.11 ± 0.25^d

6.49 ± 0.09^c

6.43 ± 0.24^b

6.25 ± 0.23^b

7

5.16 ± 0.11^a

6.40 ± 0.19^bc

7.23 ± 0.31^c

6.83 ± 0.10^bc

6.51 ± 0.39^bc

6.37 ± 0.33^bc

6.07 ± 0.33^b

14

5.18 ± 0.14^a

5.75 ± 0.10^ab*#

6.74 ± 0.35^c*

6.18 ± 0.01^bc*#

5.69 ± 0.32^ab

5.49 ± 0.10^a*#

5.49 ± 0.12^a*

1

6.27 ± 0.10^a

7.50 ± 0.15^c

8.48 ± 0.11^d

7.99 ± 0.05^d

7.43 ± 0.13^c

7.33 ± 0.31^b

7.09 ± 0.30^b

7

6.29 ± 0.10^a

6.93 ± 0.29^bc

7.15 ± 0.07^bc*

7.23 ± 0.06^c*

6.57 ± 0.04^ab*

6.73 ± 0.25^ab

6.64 ± 0.28^ab

14

6.31 ± 0.19^ab

6.49 ± 0.01^bc*

6.90 ± 0.02^c*#

7.02 ± 0.19^c*

6.45 ± 0.09^b*

5.91 ± 0.23^a*

6.07 ± 0.18^ab*

1

5.83 ± 0.29^a

7.50 ± 0.06^c

8.10 ± 0.14^d

7.99 ± 0.14^d

7.50 ± 0.14^c

6.75 ± 0.24^b

6.98 ± 0.30^b

7

5.94 ± 0.31^a

6.56 ± 0.13^a*

7.51 ± 0.13^b*

7.48 ± 0.09^b*

6.77 ± 0.18^ab*

6.65 ± 0.33^ab

6.74 ± 0.50^ab

14

5.91 ± 0.24^a

6.33 ± 0.05^a*

7.18 ± 0.14^b*

7.23 ± 0.09^b*

6.27 ± 0.28^a*

5.91 ± 0.23^a*

5.76 ± 0.26^a*

1

25.35 ± 0.99^c

21.66 ± 0.48^b

20.02 ± 0.20^a

18.82 ± 0.22^a

21.63 ± 0.52^b

21.66 ± 0.92^b

22.00 ± 0.94^b

7

25.40 ± 1.43^b

22.85 ± 0.49^a

20.23 ± 0.39^a

20.71 ± 0.20^a*

22.61 ± 0.96^a*

22.33 ± 0.95^a

22.70 ± 0.76^a

14

25.60 ± 1.33^c

25.24 ± 0.63^c*#

21.46 ± 0.42^a*#

22.40 ± 0.13^ab*#

24.40 ± 0.51^bc*

24.24 ± 0.87^bc

25.45 ± 1.08^c*

1

47.65 ± 0.70^d

40.88 ± 0.88^c

33.57 ± 1.43^a

34.98 ± 0.65^b

39.62 ± 0.47^c

37.38 ± 1.59^c

39.00 ± 1.66^c

7

47.70 ± 1.02^c

42.46 ± 0.87^b

39.27 ± 0.36^ab*

37.86 ± 0.85^a*

42.17 ± 0.25^b*

40.00 ± 1.70^ab

40.22 ± 1.71^ab

14

48.10 ± 0.40^b

47.86 ± 0.28^b*#

45.53 ± 0.40^a*#

44.20 ± 0.13^a*#

46.40 ± 0.41^ab*#

47.42 ± 2.02^ab*#

48.03 ± 2.04^b*#

1

53.98 ± 2.07^d

38.00 ± 0.15^b

34.26 ± 0.14^a

39.37 ± 0.57^b

40.22 ± 1.71^c

41.66 ± 1.77^c

43.60 ± 1.85^c

7

53.80 ± 1.46^e

44.88 ± 0.31^bc*

41.48 ± 0.51^ab*

40.69 ± 0.29^a*

44.91 ± 0.27^bc*

47.16 ± 1.86^cd

48.90 ± 2.08^d

14

54.10 ± 1.71^b

51.93 ± 0.27^b*#

44.26 ± 0.36^a*#

46.00 ± 0.19^a*#

50.27 ± 0.66^b*#

51.11 ± 2.17^b*

52.79 ± 2.25^b*