Skip to main content

Table 6 The activities of alanine and aspartate aminotransferases (ASAT and ALAT), alkaline phosphatase (ALP), and creatine kinase (CK) as well as levels of creatinine and urea in the serum of all the experimental groups, at the end of the experiments

From: Ameliorative role of a combination of chitosan, calcium, vitamins A and E against high fat diets-induced adverse effects in rats

Variables

Experimental groups

I

II

III

IV

V

ALAT activity (U/L)

27.60 ± 0.51a

63.80 ± 1.43d

61.40 ± 1.88d

54.80 ± 1.39c

44.00 ± 1.41b

–

(+ 131%)#

(− 3.8%)¶

(− 14.1%)¶

(− 31.0%)¶

 

rd = − 0.90, P < 0.001

ASAT activity (U/L)

84.00 ± 2.23a

195.60 ± 4.37d

189.80 ± 5.29d

134.40 ± 4.84c

120.20 ± 1.74b

–

(+ 133%)#

(− 3.0%)¶

(− 31.3%)¶

(− 38.5%)¶

 

rd = − 0.91, P < 0.001

ALP activity (U/L)

117.60 ± 2.16a

286.60 ± 18.10d

278.00 ± 12.41d

179.60 ± 2.93c

153.80 ± 2.91b

–

(+ 144%)#

(− 3.0%)¶

(− 37.3%)¶

(− 46.3%)¶

 

rd = − 0.91, P < 0.001

CK activity (U/L)

922.80 ± 11.97a

1153.20 ± 13.28b

1106.00 ± 32.19b

935.20 ± 41.94a

913.60 ± 40.63a

–

(+ 16.2%)#

(− 4.1%)¶

(− 18.9%)¶

(− 20.8%)¶

 

rd = − 0.68, P < 0.01

Creatinine level (mg/dL)

0.66 ± 0.04a

0.96 ± 0.05b

0.89 ± 0.03b

0.66 ± 0.05a

0.64 ± 0.02a

–

(+ 45.5%)#

(− 7.1%)¶

(− 31.3%)¶

(− 33.3%)¶

 

rd = − 0.75, P < 0.001

Urea level (mg/dL)

33.40 ± 2.16a

58.40 ± 1.50b

54.80 ± 1.39b

37.20 ± 1.62a

37.40 ± 0.87a

–

(+ 74.9%)#

(− 6.2%)¶

(− 36.3%)¶

(− 36.0%)¶

 

rd = − 0.81, P < 0.001

  1. Data is displayed as mean ± standard error of mean. P < 0.01 and P < 0.001 represent significant correlations. In the same raw, values marked with similar superscript letters are insignificantly different (P > 0.05), whereas those marked with different ones are significantly different (P < 0.05)
  2. rd: correlation coefficient between the studied variables and the administered doses of chitosan (0, 400, and 800 mg), I: control rats, II: rats fed HFD without supplements, III: rats fed HFD + supplements, IV: rats fed HFD + supplements + 400 mg chitosan and V: rats fed HFD + supplements + 800 mg chitosan
  3. #Percent of change in comparison to the group I
  4. ¶Percent of change in comparison to the group II