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Table 1 Risk and remedies of radiation therapy in various cancers

From: Recent advances in radiotherapy and its associated side effects in cancer—a review

S. no.

Type of cancer

Radiation dosage (Gy)

Associated risks

Potential Ayurvedic remedies

1

Breast cancer

45–50

Swelling and heaviness in the breast, fatigue, irritation of the skin in the targeted area, and discoloration or a bruised appearance. Problems in breastfeeding, lymphedema, acute radiation dermatitis, and a very rare cancer called as angiosarcoma

Treatment with pentoxifylline and topical purified honey ointment rescued skin-related problems (Shoma et al., 2010)

2

Head and Neck Cancer

56–66

Trouble in swallowing, soreness, hair loss, tooth decay, xerostomia, oral mucositis, altered taste sensation, nutritional deficiency, poor sleep quality, and impaired speech function

Thyme honey showed better treatment for xerostomia and mucositis (Charalambous et al., 2017).

3

Liver Cancer

70

Nausea, vomiting, gastritis, upper abdominal pain, gastric or duodenal bleeding, and fatigue

Ginger and metoclopramide treatment are efficient to treat nausea and vomiting (Sontakke, Thawani, & Naik, 2003). Arogya-wardhani used to rescue abnormal liver functions (Antarkar, 1980)

4

Non-melanoma Skin Cancer

45

Erythema, dermatitis, and atrophy

Turmeric and sandalwood containing cream can treat dermatitis (Palatty et al., 2014)

5

Thyroid Cancer

60

Swelling or pain of salivary gland, headache, vertigo, insomnia, vocal cord paralysis, fatigue, general malaise, foreign body sensation, body numbness, and urinary tract infection

Inhalation of blended 1 ml lemon and 0.5 mL of ginger essential oils showed significant improvement in salivary gland secretion (Nakayama, Okizaki, & Takahashi, 2016)

6

Colorectal Cancer

40–74

Nausea, bowel incontinence or stool leakage, fatigue, tiredness, rectal irritation, skin irritation, bladder irritation along with burning sensation or pain while urinating, diarrhea, blood in stool, vaginal irritation in women, and erection issues in men are seen

Navjeevan Rasayana, Tamra Bhasma, Swarna Bhasma, Hirak Bhasma, Agni Rasayana, Sutendra Rasayana, and Pranwallabhrasayana are improved QoL of colon cancer (Bendale et al., 2015)

7

Prostate Cancer

70.2

Radiation proctitis, rectal bleeding, diarrhea, hematochezia, radiation cystitis, impotence, fatigue, lymphedema, and erection problems

Vicenin 2 having chemo-radioprotective effect in prostate cancer cells (Malvika, Satyapal, Lal, & Mita, 2016)

8

Lung Cancer

60

Shortness of breath, difficulty in swallowing, shoulder stiffness, cough, fever, breast or nipple soreness, and radiation pneumonitis

Navjeevan Rasayana rescued laryngeal functions like voice, breathing, and swallowing (Bendale, Bendale, Birari-Gawande, Kadam, & Gund, 2015)

9

Endometrial Cancer

46

Bowel incontinence, rectal bleeding, bladder irritation, diarrhea, changes in menstruation, vaginal itching, burning, dryness, and infertility

Ficus hispida is used as an anti-inflammatory and also treat hemorrhage (Ali & Chaudhary, 2011)

10

Ovarian Cancer

22.5–33

Radiation cystitis, bowel discomfort, and vaginal irritation

Sandalwood oil and lupeol are used to treat genitourinary tract infection and cystitis (Kuvar, Lambole, Shah, Shah, & Shah, 2013; Misra & Dey, 2013)