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Table 3 Mean parentages of chromosomal aberration in spermatocyte cells of MMC-treated mice supplemented with different doses (50 and 100 mg/kg body wt) of Nitraria retusa leaf extracts at different time intervals (3 days, 1 week, and 1 month)

From: Antioxidant capacity of Nitraria retusa leaf extracts against mitomycin C-induced genetic toxicity in male mice

groups No. of examined cells Structural aberrations Total abr. Numerical variation Total num variation
Chain Ring Autosomal univalent x-y univalent N − 1 N + 1
No. % No. % No. % No. % No. No. % No. % No.
Control 250 2 0.4 1 0.2 0 0.0 2 0.4 5 2 0.66 1 0.33 3
MMC 250 14 0.27 12 0.23 11 0.21 15 0.29 52 13 0.45 16 0.55 29
MMC + NR50 3 days 250 10 0.24 11 0.26 9 0.21 12 0.29 42 9 0.41 13 0.59 22
MMC + NR100 3 days 250 9 0.24 9 0.24 8 0.22 11 0.30 37 8 0.42 11 0.58 19
MMC + NR50 1 week 250 8 0.26 7 0.23 7 0.23 8 0.27 30 6 0.40 9 0.60 15
MMC + NR100 1 week 250 6 0.28 5 0.23 5 0.23 6 0.28 21 5 0.40 6 0.60 11
MMC + NR50 1 month 250 4 0.25 3 0.19 4 0.25 5 0.31 16 4 0.57 3 0.43 7
MMC + NR100 1 month 250 3 0.23 2 0.22 2 0.22 2 0.22 9 3 0.6 2 0.4 5
  1. MMC mitomycin C, NR Nitraria retusa leaf extracts