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Table 3 Mean parentages of chromosomal aberration in spermatocyte cells of MMC-treated mice supplemented with different doses (50 and 100 mg/kg body wt) of Nitraria retusa leaf extracts at different time intervals (3 days, 1 week, and 1 month)

From: Antioxidant capacity of Nitraria retusa leaf extracts against mitomycin C-induced genetic toxicity in male mice

groups

No. of examined cells

Structural aberrations

Total abr.

Numerical variation

Total num variation

Chain

Ring

Autosomal univalent

x-y univalent

N − 1

N + 1

No.

%

No.

%

No.

%

No.

%

No.

No.

%

No.

%

No.

Control

250

2

0.4

1

0.2

0

0.0

2

0.4

5

2

0.66

1

0.33

3

MMC

250

14

0.27

12

0.23

11

0.21

15

0.29

52

13

0.45

16

0.55

29

MMC + NR50 3 days

250

10

0.24

11

0.26

9

0.21

12

0.29

42

9

0.41

13

0.59

22

MMC + NR100 3 days

250

9

0.24

9

0.24

8

0.22

11

0.30

37

8

0.42

11

0.58

19

MMC + NR50 1 week

250

8

0.26

7

0.23

7

0.23

8

0.27

30

6

0.40

9

0.60

15

MMC + NR100 1 week

250

6

0.28

5

0.23

5

0.23

6

0.28

21

5

0.40

6

0.60

11

MMC + NR50 1 month

250

4

0.25

3

0.19

4

0.25

5

0.31

16

4

0.57

3

0.43

7

MMC + NR100 1 month

250

3

0.23

2

0.22

2

0.22

2

0.22

9

3

0.6

2

0.4

5

  1. MMC mitomycin C, NR Nitraria retusa leaf extracts