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Fig. 4 | The Journal of Basic and Applied Zoology

Fig. 4

From: Possible ameliorative effect of nano-chocolate fortified with zinc on the hepatic and testicular toxicity induced by cadmium on male Swiss albino mice: histopathological and histomorphometrical studies

Fig. 4

A photomicrograph of testis sections. a Normal male Swiss albino mice showing normal histology of seminiferous tubules with complete spermatogenic layers (s). Leydig cells also showed normal appearance (LC). b1 Male Swiss albino mice treated with cadmium only showing seminiferous tubules with marked reduction of spermatogenic layers and absence of sperms (S), hyaline degeneration with esinophilic deposition, (H) and debris deposition in their lumen. Widened intertubuler areas (w) showed congested blood vessels with thickened hyalinized wall (b.v), with eosinophilia deposition (O), hemorrhage (he), and disappearances of Leydig cells (L). b2 Male Swiss albino mouse treated with cadmium only showing spermatocyte of seminiferous tubules with vacuolar nucleus (arrow) or pyknotic nucleus (arrow head). c Male Swiss albino mice treated with chocolate fortified with zinc nanoparticles showing normal seminiferous tubules with normal appearance of spermatogenesis, sperms, and Leydig cells. d Male Swiss albino mouse treated with cadmium and chocolate fortified with zinc nanoparticles showing normal histological structure of seminiferous tubules. Complete spermatogenesis and presence of sperm. Also, Leydig cells showed normal appearance (H & E X 400)

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