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Table 1 Malondialdehyde, nitric oxide, and some antioxidants levels in the renal homogenate of rats treated with CsA and FU

From: Ameliorated and antioxidant effects of Fucoidan against cyclosporine A-induced kidney injury in rats

Biomarkers

Statistic

MDA (nmol/mg protein)

NO nmol/mg protein

GSHug/mg protein

SOD U/min/mg protein

CAT U/min/mg protein

G6PD U/min/mg

protein

Group

C

Mean ± SE (n = 8)

2.06 ± 0.20

0.116 ± 0.01

1.583 ± 0.06

2.006 ± 0.12

17.68 ± 0.56

0.19 ± 0.02

CA

Mean ± SE (n = 8)

3.70 ± 0.325

0.30 ± 0.02

1.47 ± 0.11

2.28 ± 0.13

20.75 ± 1.13

0.27 ± 0.02

I or S % vs C

S = 78.87 a**

S = 16.17 a ***

I = 9.34 NS

S = 13.66 NS

S = 17.36 NS

S = 40.211 NS

CA + FU

Mean ± SE (n = 8)

3.13 ± 0.25

0.256 ± 0.02

1.872 ± 0.05

2.47 ± 0.08

20.51 ± 0.29

0.29 ± 0.04

I or S % vs C

S = 51.792 a*

S = 120.689 a***

S = 14.839 *a

S = 22.931 NS

S = 16.006 NS

S = 53.439 NS

I or S %vs CA

I = 15.140 NS

I = 13.513 NS

S = 6.070 a*

S = 8.157 NS

I = 1.156 NS

S = 9.43 NS

  1. C control group, CA Cyclosporine group, CA + FU cyclosporine + fucoidan group. The significant difference between groups was judged by ANOVA. a: significance difference between the groups, *p < 0.05; **p < 0.01; ***p < 0.001; NS non-significant, (vs C): percentage of difference with control group, (vs CA): percentage of difference with cyclosporine A group. I inhibition, S stimulation