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Table 7 Effect of C. albidum extract on levels of lipid peroxidation (LPO), superoxide dismutase (SOD), glutathione (GSH), glutathione reductase (GR), glutathione transferase (GST) and glutathione peroxidase (GPx) in the liver of diabetic rats

From: Biochemical changes in diabetic rats treated with ethanolic extract of Chysophyllum albidum fruit-skin

Treatment/group

Parameter

LPO

SOD

GSH

GR

GST

GPx

Group A (NC)

38.2 ± 4.32a

671.73 ± 52.00a

6.10 ± 0.53a

14.50 ± 0.50a

36.80 ± 4.50a

7.50 ± 0.40a

Group B (DC)

56.3 ± 8.70b

450.70 ± 50.25b

3.70 ± 0.20b

6.80 ± 0.50b

15.70 ± 1.40b

3.40 ± 0.30b

Group C (ND-200)

37.2 ± 5.45a

685.60 ± 4.80a

6.30 ± 0.50a

14.00 ± 1.40a

35.00 ± 5.50a

7.40 ± 0.60a

Group D (ND-100)

36.8 ± 5.60a

682.50 ± 6.00a

5.90 ± 0.80a

13.80 ± 1.6a

37.20 ± 6.70a

7.88 ± 0.70a

Group E (D-200)

37.4 ± 6.58a

686.46 ± 2.73a

5.80 ± 0.80a

13.05 ± 2.50a

34.70 ± 6.80a

7.20 ± 0.70a

Group F (D-100)

38.8 ± 5.55a

652.45 ± 4.70c

5.60 ± 0.60c

12.00 ± 2.00c

30.80 ± 0.40c

6.8 ± 0.63c

  1. The results are presented as mean ± SEM. Value not sharing a common superscript on the same column differ significantly (p < 0.05) from each other
  2. Units: LPO (nmole/g protein), SOD (units/g protein), GSH (μg/mg protein), GR (μmoles of GSH utilized/min/mg protein), GST (μmoles of CDNB-GSH conjugate formed/min/mg protein), GPx (μg of GSH consumed/min/mg protein). NC normal control rats: animals received distilled water in place of extract, DC diabetic control rats: animals received distilled water in place of extract, ND-200 non-diabetic rats: animals received 200 mg/kg body weight of extract. ND-100 non-diabetic rats: animals received 100 mg/kg body weight of extract, D-200 diabetic rats: animals received 200 mg/kg of extract, D-100 diabetic rats: animals received 100 mg/kg of extract