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Table 8 Effect of C. albidum extract on levels of lipid peroxidation (LPO), superoxide dismutase (SOD), glutathione (GSH), glutathione reductase (GR), glutathione transferase (GST) and glutathione peroxidase (GPx) in the kidney of diabetic rats

From: Biochemical changes in diabetic rats treated with ethanolic extract of Chysophyllum albidum fruit-skin

Treatment/group

Parameter

LPO

SOD

GSH

GR

GST

GPx

Group A (NC)

1.68 ± 0.16a

66.00 ± 5.00a

5.60 ± 0.50a

15.50 ± 0.50a

26.80 ± 3.50a

4.50 ± 0.40a

Group B (DC)

2.62 ± 0.10b

40.50 ± 5.25b

2.60 ± 0.20b

7.80 ± 0.5b

15.70 ± 0.40b

2.50 ± 0.30b

Group C (ND-200)

1.65 ± 0.25a

68.60 ± 4.00a

5.40 ± 0.50a

14.20 ± 1.40a

24.70 ± 5.30a

4.66 ± 0.67a

Group D (ND-100)

1.73 ± 0.15a

65.80 ± 5.00a

5.45 ± 0.60a

14.80 ± 0.60a

25.10 ± 4.70a

4.58 ± 0.40a

Group E (D-200)

1.76 ± 0.43a

63.46 ± 1.62a

5.80 ± 0.66a

13.70 ± 1.50a

27.30 ± 5.20a

4.42 ± 0.74a

Group F (D-100)

1.62 ± 0.18a

70.20 ± 2.00a

5.70 ± 0.80a

13.00 ± 2.40c

22.50 ± 1.50c

4.38 ± 0.65a

  1. The results are presented as mean ± SEM. Value not sharing a common superscript on the same column differ significantly (p < 0.05) from each other
  2. Units: LPO (nmole/g protein), SOD (units/g protein), GSH (μg/mg protein), GR (μmoles of GSH utilized/min/mg protein), GST (μmoles of CDNB-GSH conjugate formed/min/mg protein), GPx (μg of GSH consumed/min/mg protein). NC normal control rats: animals received distilled water in place of extract, DC diabetic control rats: animals received distilled water in place of extract, ND-200 non-diabetic rats: animals received 200 mg/kg body weight of extract. ND-100 non-diabetic rats: animals received 100 mg/kg body weight of extract, D-200 diabetic rats: animals received 200 mg/kg of extract, D-100 diabetic rats: animals received 100 mg/kg of extract