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Table 4 Effect of treatment on enzymatic activities in the liver of experimental rats

From: Toxicological effects of the concurrent administration of cadmium and arsenic through the food chain on the liver and kidney of rats

GroupParameter
CAT (μmol H2O2/min/mg protein)SOD (units/g testis)GST (μmol CDNB–GSH complex formed/min/mg protein)ASTALT
1-month exposure
 Control98.00 ± 4.04a48.50 ± 2.29a10.88 ± 1.69a39.05 ± 3.57a30.45 ± 1.23
 Cd-contaminated diet89.00 ± 2.82b (− 9.18%)28.28 ± 0.24b (− 41.69%)6.36 ± 0.10b (− 41.54%)53.31 ± 3.510b (36.52%)39.56 ± 3.15 (29.92%)
 As-contaminated diet44.70 ± 7.07c (− 54.39%)22.58 ± 0.21b (− 53.44%)3.80 ± 0.26c (− 65.07%)67.89 ± 3.134c (73.85%)57.57 ± 3.12 (89.06%)
 Cd + As-contaminated diet76.30 ± 7.63d (− 22.14%)25.75 ± 0.13b (− 46.91%)5.17 ± 0.46b (− 52.48%)59.48 ± 4.54b (52.32%)49.76 ± 0.27 (63.42%)
3-month exposure
 Control205.30 ± 4.10a46.75 ± 1.77a10.12 ± 0.04a37.00 ± 12.12a33.25 ± 1.25a
 Cd-contaminated diet189.85 ± 2.61b (− 7.53%)22.82 ± 0.02b (− 51.19%)6.12 ± 0.03b (− 39.53%)29.75 ± 6.80b (− 19.59%)21.00 ± 1.04b (− 36.84%)
 As-contaminated diet136.95 ± 2.89c (− 33.29%)11.91 ± 0.46c (− 74.52%)2.22 ± 0.88c (− 78.06%)23.75 ± 7.22c (− 35.81%)09.25 ± 3.48c (− 72.18%)
 Cd + As-contaminated diet157.35 ± 3.04d (− 23.36%)17.86 ± 0.93c (− 61.80%)4.13.02c (− 59.19%)27.25 ± 5.44b (− 26.35%)17.75 ± 2.08d (− 46.62%)
  1. Results are expressed as mean ± SD. Values not sharing the same superscript in the same column differ significantly at P < 0.05. Percentage changes are given relative to control