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Table 5 Effect of treatment on enzymatic activities in the kidney of experimental rats

From: Toxicological effects of the concurrent administration of cadmium and arsenic through the food chain on the liver and kidney of rats

Group

Parameter

CAT (μmol H2O2/min/mg protein)

SOD (units/g testis)

GST (μmol CDNB–GSH complex formed/min/mg protein)

AST

ALT

1-month exposure

  

 Control

88.70 ± 5.65a

39.75 ± 0.07a

9.01 ± 1.26a

27.06 ± 4.319a

29.01 ± 0.93

 Cd-contaminated diet

112.05 ± 2.05b (26.33%)

51.00 ± 2.10b (28.30%)

17.37 ± 3.42b (92.79%)

41.16 ± 4.26b (52.11%)

40.67 ± 1.23 (40.19%)

 As-contaminated diet

99.30 ± 2.56c (11.95%)

42.33 ± 0.18c (6.49%)

12.37 ± 0.15c (37.29%)

30.63 ± 2.81a (13.19%)

36.02 ± 0.19 (24.16%)

 Cd + As-contaminated diet

107.55 ± 2.75d (21.25%)

45.50 ± 0.03c (14.47%)

15.62 ± 0.22c (73.36%)

39.86 ± 3.24b (47.30%)

37.12 ± 0.17 (27.96%)

3-month exposure

  

 Control

177.76 ± 5.36a

44.67 ± 0.15a

9.26 ± 0.25a

32.00 ± 8.39a

29.50 ± 10.10a

 Cd-contaminated diet

101.95 ± 0.21b (− 42.65%)

16.77 ± 0.07b (− 62.46%)

3.53 ± 0.22b (− 61.88%)

22.75 ± 15.10b (-28.91%)

13.51 ± 4.41b (− 54.20%)

 As-contaminated diet

126.70 ± 4.24c (− 28.72%)

22.73 ± 0.59c (− 49.12%)

5.45 ± 0.26c (− 41.14%)

27.00 ± 8.39b (− 15.63%)

21.01 ± 0.30c (− 27.08%)

 Cd + As-contaminated diet

103.05 ± 2.21b (− 42.03%)

18.79 ± 0.05b (− 57.94%)

4.53 ± 0.53b (− 51.08%)

25.00 ± 13b (− 21.88%)

19.25 ± 4.25c (− 41.53%)

  1. Results are expressed as mean ± SD. Values not sharing the same superscript in the same column differ significantly at P < 0.05. Percentage changes are given relative to control