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Table 5 Effect of treatment on enzymatic activities in the kidney of experimental rats

From: Toxicological effects of the concurrent administration of cadmium and arsenic through the food chain on the liver and kidney of rats

GroupParameter
CAT (μmol H2O2/min/mg protein)SOD (units/g testis)GST (μmol CDNB–GSH complex formed/min/mg protein)ASTALT
1-month exposure  
 Control88.70 ± 5.65a39.75 ± 0.07a9.01 ± 1.26a27.06 ± 4.319a29.01 ± 0.93
 Cd-contaminated diet112.05 ± 2.05b (26.33%)51.00 ± 2.10b (28.30%)17.37 ± 3.42b (92.79%)41.16 ± 4.26b (52.11%)40.67 ± 1.23 (40.19%)
 As-contaminated diet99.30 ± 2.56c (11.95%)42.33 ± 0.18c (6.49%)12.37 ± 0.15c (37.29%)30.63 ± 2.81a (13.19%)36.02 ± 0.19 (24.16%)
 Cd + As-contaminated diet107.55 ± 2.75d (21.25%)45.50 ± 0.03c (14.47%)15.62 ± 0.22c (73.36%)39.86 ± 3.24b (47.30%)37.12 ± 0.17 (27.96%)
3-month exposure  
 Control177.76 ± 5.36a44.67 ± 0.15a9.26 ± 0.25a32.00 ± 8.39a29.50 ± 10.10a
 Cd-contaminated diet101.95 ± 0.21b (− 42.65%)16.77 ± 0.07b (− 62.46%)3.53 ± 0.22b (− 61.88%)22.75 ± 15.10b (-28.91%)13.51 ± 4.41b (− 54.20%)
 As-contaminated diet126.70 ± 4.24c (− 28.72%)22.73 ± 0.59c (− 49.12%)5.45 ± 0.26c (− 41.14%)27.00 ± 8.39b (− 15.63%)21.01 ± 0.30c (− 27.08%)
 Cd + As-contaminated diet103.05 ± 2.21b (− 42.03%)18.79 ± 0.05b (− 57.94%)4.53 ± 0.53b (− 51.08%)25.00 ± 13b (− 21.88%)19.25 ± 4.25c (− 41.53%)
  1. Results are expressed as mean ± SD. Values not sharing the same superscript in the same column differ significantly at P < 0.05. Percentage changes are given relative to control