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Table 6 Effect of treatment on MDA and GSH in the liver and kidney of experimental rats

From: Toxicological effects of the concurrent administration of cadmium and arsenic through the food chain on the liver and kidney of rats

Group

Parameter

Liver

Kidney

MDA (units/g tissue)

GSH (mg/g tissue)

MDA (units/g tissue)

GSH (mg/g tissue)

1-month exposure

 

 Control

57.46 ± 3.41a

22.67 ± 2.30a

47.03 ± 2.46a

21.33 ± 6.11a

 Cd-contaminated diet

62.25 ± 3.65b (8.34%)

31.33 ± 1.15b (38.20%)

74.13 ± 2.03b (57.63%)

51.00 ± 16.97b (139.10%)

 As-contaminated diet

95.21 ± 2.54c (65.70%)

42.00 ± 2.82c (85.27%)

58.88 ± 2.52c (25.20%)

48.07 ± 19.07c (125.36%)

 Cd + As-contaminated diet

75.60 ± 1.27d (31.57%)

34.33 ± 2.30b (51.43%)

69.31 ± 2.87d (47.37%)

33.09 ± 1.41d (55.13%)

3-month exposure

 

 Control

94.38 ± 1.43a

32.10 ± 2.92a

52.04 ± 2.33a

46.03 ± 4.34a

 Cd-contaminated diet

115.63 ± 1.98b (22.51%)

25.03 ± 2.64b (− 22.02%)

110.02 ± 1.97b (111.41%)

20.42 ± 2.82b (− 55.64%)

 As-contaminated diet

162.42 ± 2.75c (72.09%)

17.00 ± 5.65c (− 47.04%)

74.15 ± 0.62c (42.49%)

35.01 ± 1.41c (− 23.94%)

 Cd + As-contaminated diet

126.65 ± 2.15d (34.19%)

23.33 ± 4.04b (− 27.32%)

105.34 ± 2.94d (102.42%)

31.30 ± 2.48c (− 32.00%)

  1. Results are expressed as mean ± SD. Values not sharing the same superscript in the same column differ significantly at P < 0.05. Percentage changes are given relative to control