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Table 6 Effect of treatment on MDA and GSH in the liver and kidney of experimental rats

From: Toxicological effects of the concurrent administration of cadmium and arsenic through the food chain on the liver and kidney of rats

GroupParameter
LiverKidney
MDA (units/g tissue)GSH (mg/g tissue)MDA (units/g tissue)GSH (mg/g tissue)
1-month exposure 
 Control57.46 ± 3.41a22.67 ± 2.30a47.03 ± 2.46a21.33 ± 6.11a
 Cd-contaminated diet62.25 ± 3.65b (8.34%)31.33 ± 1.15b (38.20%)74.13 ± 2.03b (57.63%)51.00 ± 16.97b (139.10%)
 As-contaminated diet95.21 ± 2.54c (65.70%)42.00 ± 2.82c (85.27%)58.88 ± 2.52c (25.20%)48.07 ± 19.07c (125.36%)
 Cd + As-contaminated diet75.60 ± 1.27d (31.57%)34.33 ± 2.30b (51.43%)69.31 ± 2.87d (47.37%)33.09 ± 1.41d (55.13%)
3-month exposure 
 Control94.38 ± 1.43a32.10 ± 2.92a52.04 ± 2.33a46.03 ± 4.34a
 Cd-contaminated diet115.63 ± 1.98b (22.51%)25.03 ± 2.64b (− 22.02%)110.02 ± 1.97b (111.41%)20.42 ± 2.82b (− 55.64%)
 As-contaminated diet162.42 ± 2.75c (72.09%)17.00 ± 5.65c (− 47.04%)74.15 ± 0.62c (42.49%)35.01 ± 1.41c (− 23.94%)
 Cd + As-contaminated diet126.65 ± 2.15d (34.19%)23.33 ± 4.04b (− 27.32%)105.34 ± 2.94d (102.42%)31.30 ± 2.48c (− 32.00%)
  1. Results are expressed as mean ± SD. Values not sharing the same superscript in the same column differ significantly at P < 0.05. Percentage changes are given relative to control