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The Journal of Basic and Applied Zoology
Fig. 1 | The Journal of Basic and Applied Zoology

Fig. 1

From: Curcumin induces regeneration of β cells and suppression of phosphorylated-NF-κB in streptozotocin-induced diabetic mice

Fig. 1

Histological evaluation of pancreatic islets (a–f) and spleen tissues (g-l) stained with hematoxylin and eosin dyes, × 400 magnification. Pancreatic sections showed the following: a–d normal appearance of islets; e vacuolation of cells in pancreatic acini (small arrow), apoptosis of acinar epithelium (large arrow), and mononuclear inflammatory cells infiltration (arrowhead); f regular outline with normal appearance. Spleen sections showed the following: g–j normal appearance of lymphoid follicles; k lymphocytic necrosis and depletion in the splenic lymphoid follicle (arrow); l normal appearance of splenic lymphoid follicles. I, normal mice; II, mice treated with citrate; III, mice treated with DMSO; IV, mice treated with curcumin at a dose of 170 mg/kg trice a week; V, diabetic mice induced by injection with 160 mg/kg of STZ; and VI, diabetic mice treated with curcumin (170 mg/kg trice a week)

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