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Table 1 Antipyretic effect of A. amoreuxi venom using Brewer’s yeast-induced pyrexia in rats

From: Antinociceptive, antiinflammatory, and antipyretic effects induced by the venom of Egyptian scorpion Androctonus amoreuxi

Rectal temperature (TR°C) at different time intervals (h)
Treatment 0 h 1st hour 2nd hour 3rd hour 4th hour 5th hour
Yeast control 38.05 ± 0.0671 38.05 ± 0.085 38.00 ± 0.077 38.00 ± 0.052 38.00 ± 0.063 38.07 ± 0.056
Yeast + 1/10 LD50 (0.385 mg/kg)
A. amoreuxi venom
38.04 ± 0.061 35.69 ± 0.128* 36.54 ± 0.318* 37.08 ± 0.157* 36.925 ± 0.170* 37.09 ± 0.340*
Yeast + 1/5 LD50 (0.77 mg/kg)
A. amoreuxi venom
38.09 ± 0.051 35.55 ± 0.159* 36.08 ± 0.364* 36.25 ± 0.194* 36.93 ± 0.330* 37.03 ± 0.33*
Yeast + metamizol
(5 mg/kg)
38.01 ± 0.055 36.85 ± 0.146*# 36.30 ± 0.168*# 36.25 ± 0.199*# 36.43 ± 0.067*# 36.80 ± 0.207*#
  1. Data are presented as mean ± SEM (6 animals /group)
  2. *A significant difference between yeast control and treated groups using Student’s unpaired t test (p < 0.05)
  3. #A significant difference between all groups at time intervals using one-way ANOVA (p ≤ 0.05)