TY - JOUR AU - Fagbohun, Ifeoluwa Kayode AU - Idowu, Emmanuel Taiwo AU - Olakiigbe, Abiodun Kanmi AU - Oyeniyi, Amos Tolulope AU - Otubanjo, Olubunmi Adetoro AU - Awolola, Taiwo Samson PY - 2020 DA - 2020/09/29 TI - Metabolic resistance mechanism in Aedes aegypti from Lagos State, Nigeria JO - The Journal of Basic and Applied Zoology SP - 59 VL - 81 IS - 1 AB - Aedes aegypti transmits several arboviral diseases of global public health threat such as dengue, zika, and yellow fever. Recently, a series of yellow fever outbreaks have been reported in different parts of the country. Globally, the control of mosquito-borne diseases has relied heavily on insecticides based vector control efforts. Therefore, we assessed the susceptibility status to three different classes of WHO approved insecticides and evaluated the importance of detoxifying enzymes on insecticides resistance in Aedes aegypti collected from Lagos State, Nigeria. Aedes aegypti immature stages were collected from suitable habitats in peri-domestic areas of Alimosho, Kosofe, Badagry, and Ibeju-Lekki Local Government Areas (LGAs) of Lagos State, 2–5 days old glucose-fed adult female mosquitoes were exposed to discriminating doses of DDT, permethrin, bendiocarb, and PBO synergist using WHO standard procedure and kits. Identification was through morphological means only. SN - 2090-990X UR - https://doi.org/10.1186/s41936-020-00194-8 DO - 10.1186/s41936-020-00194-8 ID - Fagbohun2020 ER -