Fig. 3

Photomicrographs of liver tissues for fibrosis evaluation in all rat groups, stained with Masson's trichrome stain. a Control group showing the normal architecture of the liver, with hepatic strands (HS) around the central vein (CV) (scale bar 20 μm). b (TvE) group showing the normal architecture of the liver, with hepatic strands (HS) around the central vein (CV) (scale bar 20 μm). c ANIT group showing severe fibrosis (F) around hepatic vein and hepatic artery (A), congestion (C) in hepatic vein and leukocytes infiltration (LI) (scale bar = 50 μm). d ANIT + TvE group showing the normal architecture of the liver, with hepatic strands (HS) around the central vein (CV) (scale bar = 50 μm). e ANIT + UDCA group showing normal hepatic strands (HS) around the central vein (CV) and mild bleeding (scale bar = 20 μm). f ANIT + AIE + UDCA group showing the normal architecture of the liver, with hepatic lobules around the central vein (CV) and each lobule consisting of hepatic strands (HS) of hepatocytes (scale bar 50 μm)