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Fig. 8 | The Journal of Basic and Applied Zoology

Fig. 8

From: Protective effects of Zingiber officinale extract on myocardium and placenta against labetalol-induced histopathological, immune-histochemical, and ultrastructural alterations in pregnant rats

Fig. 8

An electron photomicrographs of the placenta (GD 20) of female rats: a Control labyrinth showing normal structure of the feto-maternal barrier, I, II and III trophoblastic layers, cytotrophoblasts (Cy), fetal capillary (FC), endothelium (E) and maternal sinusoids (MS); b control basal cells with normal euchromatic nucleus (N), Nucleolus (Nu) and homogenous cytoplasm; c, d normal labyrinth and basal cells of placenta of ginger group; e–h labyrinth cells of labetalol-administrated group showing many destructive changes including degenerated nuclei (arrow head) of the trophoblast of labyrinth wall, small droplets (Arrow), fragmentation of maternal sinusoids which filled with red blood cells (RBCs), rarified cytoplasm (*), many lysosomes, pyknotic nucleus (N) of endothelium of fetal capillary (FC) and degenerated mitochondria (M), i, j basal cells of labetalol-administrated placenta showing apoptotic spongiotrophoblast cells with pyknotic, vacuolated and fragmented nuclei (arrow head), k, l labetalol + ginger placenta showing normal structure. Scale bar = 5.0 µm (a–d, g, k, l), 10.0 µm (f), 2.0 µm (e, h, i, j)

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