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The Journal of Basic and Applied Zoology
Fig. 2 | The Journal of Basic and Applied Zoology

Fig. 2

From: Protective effects of some antioxidants against long-term intake of aspartame toxicity on liver and kidney: biochemical and histopathological approach in rats

Fig. 2

Photomicrographs of kidney section from male and female rats, respectively, of A control male rat and B control rat showing normal renal tubules (rt) and glomeruli (g); B rats from groups treated with aspartame showing degeneration (d) of the glomerular tuft with necrosis (n) of the renal tubular epithelial cells; C rats from groups treated with aspartame and garlic showing interstitial edema (e) in both cortex and medulla with perivascular inflammatory (i) cell reactions; D rats from groups treated with aspartame and melatonin showing more or less normal tubular and glomerular structure with mild interstitial edema (e); E rats from groups treated with aspartame and thymoquinone showing more or less normal tubular and glomerular structure; and F rats from groups treated with aspartame and melatonin plus thymoquinone showing normal histological structure of renal glomeruli and tubules in the renal cortex (H&E) (×10 ×10)

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