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The Journal of Basic and Applied Zoology
Fig. 1 | The Journal of Basic and Applied Zoology

Fig. 1

From: Polyphenolic-enriched olive leaf extract attenuated doxorubicin-induced cardiotoxicity in rats via suppression of oxidative stress and inflammation

Fig. 1

Cardio protective effect of OL against DOX-induced cardiac damage, A serum cardiac injury markers: AST and CK activities in serum. Data are represented as mean ± S.E.M. of six rats of each of the groups. a P < 0.05 versus control; b P < 0.05 versus DOX. B Histopathological changes. Light micrographs of heart sections from control rats (a) showing normal heart architecture, heart sections from DOX groups (b & c) showing focal necrosis with eosinophilic cytoplasm and pyknotic nuclei (thick arrow) and degeneration of myocardial fibers (thin arrow), and inflammatory cell infiltration (*). In the micrographs from DOX + LD of OL group (d) and DOX + MD of OL group (e) showing some eosinophilic cytoplasm and pyknotic nuclei and degeneration of myocardial fibers. 400 × magnification

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