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Table 1 Effect of hydroethanolic extract of Cassia spectabilis leaves on the serum enzyme activities in DF-treated rats

From: Influence of hydroethanolic extract of Cassia spectabilis leaves on diclofenac-induced oxidative stress and hepatorenal damage in Wistar rats

Treatment groups Serum enzyme activities as markers of liver injuries in rats
ALT (U/L) AST (U/L) ALP (U/L) GGT (U/L) LDH (U/L)
1. Normal control 11.7 ± 1.0 15.5 ± 0.8 117.8 ± 1.4 26.6 ± 0.9 13.5 ± 2.7
2. DF control 32.3 ± 1.1a 47.3 ± 0.8a 384.7 ± 1.7a 95.5 ± 1.4a 40.5 ± 4.2a
3. DF + 100 mg CSE 24.4 ± 0.4ab 32.9 ± 0.7ab 267.8 ± 1.0ab 75.2 ± 0.9ab 37.7 ± 1.7a
4. DF + 300 mg CSE 28.2 ± 0.4ab 37.7 ± 0.6ab 277.6 ± 0.6ab 81.9 ± 0.6ab 40.5 ± 2.9a
5. DF + 500 mg CSE 15.2 ± 0.4ab 20.7 ± 0.6ab 234.9 ± 1.2ab 57.5 ± 0.6ab 29.7 ± 1.7ab
  1. Values are Mean ± SEM, n = 6
  2. DF diclofenac sodium, CSE hydroethanolic extract of Cassia spectabilis leaf (mg/kg body weight), ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma glutamyl transferase, LDH lactate dehydrogenase
  3. aSignificantly different from the normal control (p < 0.05)
  4. bSignificantly different from the DF control (p < 0.05)