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Table 3 Effect of hydroethanolic extract of Cassia spectabilis leaves on the serum levels of renal injury markers in DF-treated rats

From: Influence of hydroethanolic extract of Cassia spectabilis leaves on diclofenac-induced oxidative stress and hepatorenal damage in Wistar rats

Treatment groups

Serum levels of the markers of renal injuries in rats

Creatinine (µmol/L)

Urea (mmol/L)

Uric acid (µmol/L)

1. Normal control

78.08 ± 0.80

5.64 ± 0.25

205.82 ± 1.96

2. DF control

457.73 ± 8.25a

28.34 ± 0.77a

489.91 ± 3.07a

3. DF + 100 mg/kg CSE

215.03 ± 0.89ab

22.51 = 0.76ab

441.97 ± 0.69ab

4. DF + 300 mg/kg CSE

224.66 ± 0.59ab

26.53 ± 0.51ab

449.27 ± 0.37ab

5. DF + 500 mg/kg CSE

172.48 ± 1.96ab

13.77 ± 0.44ab

425.83 ± 4.39ab

  1. Values are Mean ± SEM, n = 6
  2. DF diclofenac sodium, CSE Cassia spectabilis leaf extract
  3. aSignificantly different from the normal control (p < 0.05)
  4. bSignificantly different from the diclofenac control (p < 0.05)