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Table 3 Effect of hydroethanolic extract of Cassia spectabilis leaves on the serum levels of renal injury markers in DF-treated rats

From: Influence of hydroethanolic extract of Cassia spectabilis leaves on diclofenac-induced oxidative stress and hepatorenal damage in Wistar rats

Treatment groups Serum levels of the markers of renal injuries in rats
Creatinine (µmol/L) Urea (mmol/L) Uric acid (µmol/L)
1. Normal control 78.08 ± 0.80 5.64 ± 0.25 205.82 ± 1.96
2. DF control 457.73 ± 8.25a 28.34 ± 0.77a 489.91 ± 3.07a
3. DF + 100 mg/kg CSE 215.03 ± 0.89ab 22.51 = 0.76ab 441.97 ± 0.69ab
4. DF + 300 mg/kg CSE 224.66 ± 0.59ab 26.53 ± 0.51ab 449.27 ± 0.37ab
5. DF + 500 mg/kg CSE 172.48 ± 1.96ab 13.77 ± 0.44ab 425.83 ± 4.39ab
  1. Values are Mean ± SEM, n = 6
  2. DF diclofenac sodium, CSE Cassia spectabilis leaf extract
  3. aSignificantly different from the normal control (p < 0.05)
  4. bSignificantly different from the diclofenac control (p < 0.05)