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Table 5 Effect of hydroethanolic extract of Cassia spectabilis leaves on the serum antioxidant enzyme activities in DF-treated rats

From: Influence of hydroethanolic extract of Cassia spectabilis leaves on diclofenac-induced oxidative stress and hepatorenal damage in Wistar rats

Treatment groups

Serum antioxidant enzyme activities in rats

SOD (U/mg p)

CAT (U/mg p)

GPx (U/mg p)

GST (U/mg p)

1. Normal control

11.36 ± 0.43

10.43 ± 0.29

10.25 ± 0.37

41.15 ± 1.06

2. DF control

4.16 ± 0.27a

2.24 ± 0.19a

2.83 ± 0.19a

15.18 ± 0.53a

3. DF + 100 mg CSE

4.66 ± 0.19a

5.27 ± 0.32ab

5.38 ± 0.28ab

22.29 ± 0.68ab

4. DF + 300 mg CSE

6.64 ± 0.19ab

6.60 ± 0.21ab

4.46 ± 0.18ab

19.35 ± 0.41ab

5. DF + 500 mg CSE

9.17 ± 0.36b

6.52 ± 0.25ab

5.49 ± 0.41ab

32.21 ± 0.74ab

  1. Values are Mean ± SEM, n = 6
  2. DF diclofenac sodium, CSE Cassia spectabilis leaf extract, SOD superoxide dismutase, CAT catalase, GPx glutathione peroxidase, GST glutathione S-transferase, P protein
  3. aSignificantly different from the normal control (p < 0.05)
  4. bSignificantly different from the diclofenac control (p < 0.05)