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Table 5 Effect of hydroethanolic extract of Cassia spectabilis leaves on the serum antioxidant enzyme activities in DF-treated rats

From: Influence of hydroethanolic extract of Cassia spectabilis leaves on diclofenac-induced oxidative stress and hepatorenal damage in Wistar rats

Treatment groups Serum antioxidant enzyme activities in rats
SOD (U/mg p) CAT (U/mg p) GPx (U/mg p) GST (U/mg p)
1. Normal control 11.36 ± 0.43 10.43 ± 0.29 10.25 ± 0.37 41.15 ± 1.06
2. DF control 4.16 ± 0.27a 2.24 ± 0.19a 2.83 ± 0.19a 15.18 ± 0.53a
3. DF + 100 mg CSE 4.66 ± 0.19a 5.27 ± 0.32ab 5.38 ± 0.28ab 22.29 ± 0.68ab
4. DF + 300 mg CSE 6.64 ± 0.19ab 6.60 ± 0.21ab 4.46 ± 0.18ab 19.35 ± 0.41ab
5. DF + 500 mg CSE 9.17 ± 0.36b 6.52 ± 0.25ab 5.49 ± 0.41ab 32.21 ± 0.74ab
  1. Values are Mean ± SEM, n = 6
  2. DF diclofenac sodium, CSE Cassia spectabilis leaf extract, SOD superoxide dismutase, CAT catalase, GPx glutathione peroxidase, GST glutathione S-transferase, P protein
  3. aSignificantly different from the normal control (p < 0.05)
  4. bSignificantly different from the diclofenac control (p < 0.05)