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Table 6 Effect of hydroethanolic extract of Cassia spectabilis leaves on the levels of serum MDA, GSH and G6Pase in DF-treated rats

From: Influence of hydroethanolic extract of Cassia spectabilis leaves on diclofenac-induced oxidative stress and hepatorenal damage in Wistar rats

Treatment groups Levels of hepatorenal oxidative damage markers in rats
G6Pase (ng/µL) MDA (nmol/mg p) GSH (µg/mL)
1. Normal control 33.89 ± 0.91 3.46 ± 0.20 64.44 ± 1.05
2. DF control 14.71 ± 0.44a 14.44 ± 0.73a 30.13 ± 0.86a
3. DF + 100 mg/kg CSE 20.98 ± 0.71ab 7.49 = 0.44ab 37.13 ± 0.53ab
4. DF + 300 mg/kg CSE 17.01 ± 0.59ab 7.25 ± 0.24ab 36.05 ± 0.80ab
5. DF + 500 mg/kg CSE 27.26 ± 0.80ab 4.74 ± 0.18b 47.54 ± 0.74ab
  1. Values are Mean ± SEM, n = 6
  2. DF diclofenac sodium, CSE Cassia spectabilis leaf extract, G6Pase glucose 6-phosphatase, MDA malon dialdehyde, GSH reduced glutathione
  3. aSignificantly different from the normal control (p < 0.05)
  4. bSignificantly different from the diclofenac control (p < 0.05)