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The Journal of Basic and Applied Zoology
Fig. 5 | The Journal of Basic and Applied Zoology

Fig. 5

From: Possible ameliorative effect of human placental extract on methotrexate-induced nephrotoxicity in albino rats

Fig. 5

(A–D) photomicrographs from kidney sections showing caspase-3 expression in (A&B) control and HPE-treated rats, respectively showing caspase-3 expression as brown color in few nuclei (arrows), (C) MTX-treated rat showing caspase-3 expression in large number of nuclei (arrows) and (D) MTX and HPE-treated rat showing caspase-3 expression in few nuclei (arrows), (caspase-3 immunostain, counterstained with hematoxylin). (E) Caspase-3 expression in the different experimental groups. (***): highly significant at p < 0.001 compared with the control group. (*): significant at p < 0.05 compared with the control group. (c): significant at p < 0.05 compared with MTX group

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