Antagonistic role of barley against bioaccumulation and oxidative stress of aflatoxin B1 in male rats

Elgohary, Mohamed Ramadan; Abdel-Fattah, Shaaban Mostafa; Abu-Sree, Yehia Hassan; Morsy, Gamal Mohamed; Ali, Atef Abdel-Moneem

doi:10.1186/s41936-022-00309-3

The Journal of Basic and Applied Zoology

Table 6 The activity of catalase (CAT, U/ml), superoxide dismutase (SOD, U/ml), and glutathione reductase (GR, U/ml) in serum of rats in groups I to V, after 1, 7, 14 and 21 days of administration

From: Antagonistic role of barley against bioaccumulation and oxidative stress of aflatoxin B1 in male rats

Experimental groups	Experimental periods (in days)				One-way ANOVA	Regression analysis	r
Experimental groups	1 day	7 days	14 days	21 days	One-way ANOVA	Regression analysis	r
CAT
Group I	2.8 ± 0.032^aC	2.88 ± 0.037^aC	2.82 ± 0.037^aC	2.88 ± 0.037^aC	F_3,16(0.05) = 1.31, P ≥ 0.05	NR	NC
Group II	2.82 ± 0.037^aC	2.80 ± 0.032^aC	2.80 ± 0.032^aC	2.80 ± 0.032^aC	F_3,16(0.05) = 0.91, P ≥ 0.05	NR	NC
Group III	2.86 ± 0.051^aC	2.86 ± 0.051^aC	2.92 ± 0.058^aC	2.88 ± 0.066^aC	F_3,16(0.05) = 0.246, P ≥ 0.05	NR	NC
Group IV	2.28 ± 0.037^dA	1.98 ± 0.058^cA	1.7 ± 0.071^bA	1.38 ± 0.058^aA	F_3,16(0.05) = 44.9, P < 0.05	y = −0.044x + 2.31	−0.99*
Group V	2.42 ± 0.058^aB	2.47 ± 0.058^aB	2.39 ± 0.073^aB	2.49 ± 0.037^aB	F_3,16(0.05) = 1.733, P ≥ 0.05	NR	NC
One-way ANOVA	F_4.20(0.05) = 45.6	F_4.20(0.05) = 79.8	F_4.20(0.05) = 101.2	F_4.20(0.05) = 191.8	–	–	–
P-value	P < 0.05	P < 0.05	P < 0.05	P < 0.05	–	–	–
SOD
Group I	157.8 ± 0.37^aBC	156.0 ± 0.95^aB	156.6 ± 1.14^aB	157.0 ± 1.18^aBC	F_3,16(0.05) = 0.691, P ≥ 0.05	NR	NC
Group II	155.0 ± 1.76^aB	157.8 ± 0.37^aB	157.8 ± 0.37^aB	157.8 ± 0.37^aBC	F_3,16(0.05) = 0.091, P ≥ 0.05	NR	NC
Group III	160.4 ± 1.24^aC	158.6 ± 1.86^aB	157.4 ± 1.39^aB	160.6 ± 1.39^aC	F_3,16(0.05) = 2.09, P ≥ 0.05	NR	NC
Group IV	141.0 ± 1.05^dA	135.6 ± 0.98^cA	128.6 ± 0.93^bA	119.6 ± 1.21^aA	F_3,16(0.05) = 78.2, P < 0.05	y = −1.07x + 142.7	−0.99*
Group V	156.0 ± 0.8^aBC	155.6 ± 0.84^aB	156.0 ± 0.66^aB	155.8 ± 0.80^aB	F_3,16(0.05) = 0.056, P ≥ 0.05	NR	NC
One-way ANOVA	F_4.20(0.05) = 54.1	F_4.20(0.05) = 113.0	F_4.20(0.05) = 276.1	F_4.20(0.05) = 421.4	–	–	–
P-value	P < 0.05	P < 0.05	P < 0.05	P < 0.05	–	–	–
GR
Group I	36.0 ± 0.84^aB	37.2 ± 1.16^aB	38.0 ± 0.95^aB	37.6 ± 0.98^aBC	F_3,16(0.05) = 0.766, P ≥ 0.05	NR	NC
Group II	38.2 ± 0.86^aB	36.0 ± 0.84^aB	36.0 ± 0.84^aB	36.1 ± 0.84^aB	F_3,16(0.05) = 1.704, P ≥ 0.05	NR	NC
Group III	40.0 ± 1.18^aB	39.8 ± 1.24^aB	40.4 ± 1.12^aB	40.4 ± 1.03^aC	F_3,16(0.05) = 0.068, P ≥ 0.05	NR	NC
Group IV	31.6 ± 0.93^cA	27.0 ± 0.71^bA	23.8 ± 0.58^aA	21.2 ± 0.58^aA	F_3,16(0.05) = 47.3, P < 0.05	y = 32.36e^−0.0215	–0.98*
Group V	36.1 ± 0.68^aB	38.2 ± 0.84^aB	40.0 ± 0.84^aB	36.0 ± 0.51^aB	F_3,16(0.05) = 0.672, P ≥ 0.05	NR	NC
One-way ANOVA	F_4.20(0.05) = 8.76	F_4.20(0.05) = 26.2	F_4.20(0.05) = 50.1	F_4.20(0.05) = 73.02	–	–	–
P-value	P < 0.05	P < 0.05	P < 0.05	P < 0.05	–	–	–

Data represented as a mean ± SEM
NR no significant relationship between experimental period and antioxidant enzyme activity; NC no significant correlation coefficient (r)
^{a, b, c, d}: in the same row (Group), averages labeled with the same small letter are similar (insignificant, P ≥ 0.05), while others aren’t (P < 0.05)
^{A, B}: in the same column (period), averages labeled with the same capital letter are similar (insignificant, P ≥ 0.05), while others aren’t (P < 0.05)

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