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The Journal of Basic and Applied Zoology
Fig. 4 | The Journal of Basic and Applied Zoology

Fig. 4

From: Gentiana lutea attenuates hepatotoxicity induced by ketoconazole in rats by fortifying the cellular antioxidant defense system

Fig. 4

Photomicrographs of liver sections in central area (a) and portal area (b) from control rats showing the normal arrangement of hepatocytes. Liver section of KET-treated rats (c) showing extensive degeneration of hepatocytes (thin arrows), focal necrosis (thick arrows), and inflammatory cell infiltration * in central vein (cv) and portal area p (d). Group of rats pretreated with GEN before KET (e, f) exhibiting relatively normal appearance of hepatocytes with moderate degeneration and focal vacuolated cells (H&E, X 400)

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