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The Journal of Basic and Applied Zoology
Fig. 7 | The Journal of Basic and Applied Zoology

Fig. 7

From: Gentiana lutea attenuates hepatotoxicity induced by ketoconazole in rats by fortifying the cellular antioxidant defense system

Fig. 7

The overview of cellular oxidative stress and toxicity in liver tissue of rats after ketoconazole treatment. The speculative pathway indicates the hepatotoxicity effect of ketoconazole attributed to oxidative damage to hepatic proteins, lipids, and DNA, and depletions in natural antioxidants (SOD, CAT), while Gentiana prevented the hepatotoxicity of ketoconazole via its antioxidant effects (fragmented arrows)

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