Fig. 2

Photomicrograph of testis section staining with H&E, X200. a From normal male Swiss albino mouse showing normal histological structure of seminiferous tubules including complete spermatogenic layers (ST) and Leydig cells (L). b Sections of testis from male Swiss albino mice treated with gentamicin showed loss of normal architecture of seminiferous tubules (st), disturbed of spermatogenic layers, absence of sperm and marked degenerative changes with exfoliated spermatogenic cells in the lumen (ST). Distracted basal liminal of seminiferous tubules (double arrow head). b1 from male Swiss albino mice treated with gentamicin only showing hyaline degeneration with eosinophilia deposition (H), cystic degeneration (c) and scattered pyknotic nuclei in the basal cell layers in seminiferous tubules (st). A widened interstitial space (w) and moderate reduction in spermatogenic series and reduction of sperms in othors seminiferous tubules (st) were seen. b2 Sections of the testis from male Swiss albino mice treated with gentamicin showing diffused seminiferous tubules with moderate to marked degenerative changes and reduction in spermatogenic layers with absence of sp seminiferous tubules erm (st). c From male mice treated with gentamicin- Trigonella foenum-graecum showing normal appearance of some seminiferous tubules (st), while mild reduction in spermatogenic layers and absence of sperm in lumens of othors scattered seminiferous tubules still showed (st star). d From male mice treated with mice treated with gentamicin-germinated Trigonella foenum-graecumshowed normal histological structures of layers of seminiferous tubules (st) and normal appearance of Leydig cells (L)