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Table 8 Effect of polyherbal formula (LACTN) on some oxidative stress markers of urolithiatic rats

From: Antiurolithiatic effect of a polyherbal formulation against sodium oxalate-induced urolithiasis in rats

Parameters

Groups

Prophylactic

Curative

Control

Urolithiatic

Urolithiatic  +  LACTN

Urolithiatic  +  Cystone

Control

Urolithiatic

Urolithiatic  +  LACTN

Urolithiatic  +  Cystone

MDA (nM/g. tissue)

18.475  ±  1.111a

37.872  ±  1.633b

27.351  ±  1.824c

21.242  ±  0.954c

22.888  ±  0.861a

41.778  ±  1.892b

24.975  ±  0.873a

25.323  ±  0.782a

GSH (mg/g. tissue)

4.833  ±  0.439a

1.817  ±  0.079b

4.667  ±  0.246a

5.000  ±  0.208a

8.084  ±  0.170a

4.717  ±  0.244b

7.501  ±  0.227ac

7.132  ±  0.2186c

GST (U/g. tissue)

53.333  ±  2.445a

21.833  ±  1.470b

52.483  ±  1.804a

52.733  ±  0.884a

49.804  ±  3.272a

29.263  ±  0.887b

47.105  ±  0.957a

47.583  ±  0.546a

SOD (U/g. tissue)

742.333  ±  9.636ac

458.833  ±  10.928b

765.643  ±  14.582c

699.167  ±  24.844a

666.500  ±  19.056a

392.000  ±  27.995b

700.220  ±  15.338a

703.500  ±  23.906a

CAT (U/g. tissue)

0.530  ±  0.017a

0.290  ±  0.024b

0.510  ±  0.018a

0.498  ±  0.011a

0.916  ±  0.107a

0.398  ±  0.017b

0.980  ±  0.029a

0.654  ±  0.049c

  1. Values are expressed as mean ± SEM (n = 6). ANOVA post hoc with Duncan’s test was performed to compare between groups. Values with different row superscript letters of the same regimen are significantly different (P < 0.05)