Fig. 2

a Photomicrograph of control testis showing normal testicular architecture with an orderly arrangement of differentiating spermatogenic and sertoli cells in the wall of these miniferous tubules and Leydig cells in the interstitial space (H&E ×400). b Photomicrograph of testis section from treated rat of low dose showing separation of germinal epithelia of seminiferous tubules (black arrow with two heads) and congestion of interstitial spaces with blood (black arrow) (H&E ×200). c Enlarged section of b showing detached degenerative primary spermatogonia from the wall of seminiferous tubules (black arrow with two heads), congested interstitial artery (star), and thickening of its wall (black arrow) (H&E ×400). d Photomicrograph of testis section from treated rat of high dose showing separation and destruction of walls of seminiferous tubules (black arrow with two heads) (H&E ×200). e Photomicrograph of testis section from treated rat of high dose showing pinkish edematous fluid between seminiferous tubules (black arrow) and arrest of spermatogenic layers of seminiferous tubules (black arrow with two heads) (H&E ×400)