Fig. 5
From: Ketorolac- and warfarin-induced renal toxicity: ultrastructural and biochemical study
Electron micrographs of the rat cortex of KT/WR group. a The glomerular podocyte with hypertrophic processes (P), dilated blood capillaries (c), and damaged plasma membranes (arrow). b Lining cells of PCT and DCT appeared with varying degrees of vacuolation and fragmentation, microvilli (Mv), mitochondria (M), lysosomes (L), and damaged plasma membrane (arrow). c PCT with severe vacuolated cells (V) and damaged mitochondria (M), and glomerulus with dilated blood capillary (C) and stretched electron dense podocytic processes (P). d Higher magnification of PCT with vacuolated nucleus (N), damaged disorganized mitochondria (M), many lysosomes (L), and fragmented basal enfolding (arrow) (scale bar = 2 μm)