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Table 4 Effect of C. albidum extract on levels of plasma glucose, insulin, creatinine and aminotransferases of diabetic rats

From: Biochemical changes in diabetic rats treated with ethanolic extract of Chysophyllum albidum fruit-skin

Treatment/group

Parameter

Glucose

Insulin

Creatinine

ALT

AST

Group A (NC)

185 ± 18.30a

14.30 ± 0.50a

13.09 ± 0.84a

86.50 ± 6.70a

170.28 ± 25.22a

Group B (DC)

280.50 ± 20.56b

6.40 ± 0.42b

28.84 ± 0.12b

158.00 ± 10.20b

350.28 ± 34.40b

Group C (ND-200)

155.70 ± 15.60c

13.24 ± 0.54a

12.37 ± 0.35a

88.70 ± 10.30a

185.55 ± 50.61a

Group D (ND-100)

169.35 ± 14.20a

13.20 ± 0.40a

11.99 ± 0.12a

80.85 ± 18.60a

165.85 ± 14.52a

Group E (D-200)

230.30 ± 21.63d

10.80 ± 0.60c

15.95 ± 0.23c

105.75 ± 8.50c

195.40 ± 42.10c

Group F (D-100)

255.58 ± 22.26e

10.45 ± 0.50c

20.06 ± 2.29d

130.60 ± 10.20d

230.30 ± 15.6d

  1. The results are presented as mean ± SEM. Value not sharing a common superscript on the same column differ significantly (p < 0.05) from each other
  2. Values for plasma glucose and creatinine are given as mg/Dl, while aminotransferases and insulin are in units/ml and ng/ml respectively. NC normal control rats: animals received distilled water in place of extract, DC diabetic control rats: animals received distilled water in place of extract, ND-200 non-diabetic rats: animals received 200 mg/kg body weight of extract, ND-100 non-diabetic rats: animals received 100 mg/kg body weight of extract, D-200 diabetic rats: animals received 200 mg/kg of extract, D-100 diabetic rats: animals received 100 mg/kg of extract