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Table 3 Effect of A. australis venom on biochemical and antioxidant parameters of EAC-bearing mice

From: Antitumor efficacy of the Egyptian Scorpion Venom Androctonus Australis: in vitro and in vivo study

Parameter treatment

Urea (mg/dL)

Creatinine (mg/dL)

Glucose (mg/dL)

Cholesterol (mg/dL)

CAT (U/g tissue)

SOD (U/g tissue)

GSH (mg/g tissue)

Normal control

29.60 ± 1.06

0.10 ± 0

141.00 ± 2.16

74.20 ± 1.30

0.8 ± 0.03

149.76 ± 2.44

0.36 ± 0.04

EAC control

84.90* ± 3.78

0.27* ± 0.03

238.67* ± 3.76

81.27* ± 2.79

0.74 ± 0.02

130.5 ± 2.82

0.32 ± 0.01

EAC + 1/10 LD50 (0.025 mg/kg BW)

48.55# ± 3.78

0.26 ± 0.03

221.05# ± 4.68

73.82# ± 2.12

0.82 ± 0.02

165.766 ± 4.64

0.38 ± 0.05

EAC + cisplatin (2 mg/Kg BW)

30.68# ± 2.93

0.23 ± 0.02

256.30 ± 3.45

76.58 ± 2.97

0.8 ± 0.07

473.04## ± 4.9

0.38 ± 0.02

  1. Results are expressed as mean ± SE (n = 7)
  2. *Significant difference between normal control and EAC control using unpaired t test (P < 0.05)
  3. #Significant difference between EAC control and treated groups using one-way ANOVA followed by the post hoc Duncan test (P < 0.05).