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Table 2 Antiinflammatory effect of A. amoreuxi venom using Brewer’s yeast-induced paw oedema in rats

From: Antinociceptive, antiinflammatory, and antipyretic effects induced by the venom of Egyptian scorpion Androctonus amoreuxi

Paw thickness (cm)
Treatment Initial After 3 h After 6 h
Yeast control 0.869 ± 0.029 0.825 ± 0.02 0.8 ± 0.031
Yeast + 1/10 LD50 (0.385 mg/kg) A. amoreuxi venom 0.894 ± 0.023 0.894 ± 0.023
(6.788)
0.693 ± 0.020*
(13.375)
Yeast + 1/5 LD50 (0.77 mg/kg)
A. amoreuxi venom
0.888 ± 0.026 0.756 ± 0.017*
(8.364)
0.669 ± 0.019*
(16.375)
Yeast + diclofenac
sodium (20 mg/kg)
0.825 ± 0.015 0.719 ± 0.024*#
(12.848)
0.638 ± 0.018*#
(20.25)
  1. Data are presented as mean ± SEM (6 animals/group)
  2. *A significant difference between yeast control and treated groups using Student’s unpaired t test (p < 0.05)
  3. #A significant difference between all groups at time intervals (3 and 6 h) using one-way ANOVA (p ≤ 0.05). Values between brackets represent percentage of inflammation inhibition