Fig. 2

Photomicrographs of liver tissues in all rat groups stained by hematoxylin and eosin (H&E staining). a Control group showing the normal architecture of the liver with hepatic lobules around the central vein (CV) and each lobule consisting of hepatic strands (HS) of hepatocytes (scale bar = 50 μm). b (TvE) group showing normal hepatic strands (HS) of hepatocytes around the central vein (CV) (scale bar = 20 μm). c (C.a) ANIT group showing leukocytes infiltration (LI), fibrosis (F), bilirubin pigment (BP), and congestion (C) in the bile duct (BD). (C.b) showing vaculated cells (V) and severe congestion (C) in central vein (CV). (C.c) showing bilirubin pigment (BP) (scale bar a = 20 μm, b = 50 μm, c = 20 μm). d ANIT + TvE group showing mild hydropic degeneration of hepatocytes around the central vein (CV), bleeding (BL), and leukocytic in filtration (LI) (scale bar = 20 μm). e ANIT + UDCA group showing normal hepatocytes and mild congestion of central vein (cv) (scale bar = 20 μm). f ANIT + AIE + UDCA group showing the normal architecture of the liver, with hepatic lobules around the central vein (CV) and each lobule consisting of hepatic strands (HS) of hepatocytes (scale bar 20 μm)