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The Journal of Basic and Applied Zoology
Fig. 2 | The Journal of Basic and Applied Zoology

Fig. 2

From: Proanthocyanidin and sodium butyrate synergistically modulate rat colon carcinogenesis by scavenging free radicals and regulating the COX-2 and APC pathways

Fig. 2

A Average total numbers of ACF observed in the colons of rats from all experimental groups; *significance versus G1 at P < 0.05; **significance vs. G2 and G3 at P < 0.05 (ANOVA); samples from 10 rats/group were subjected to the ACF analysis assay. B–I Photomicrographs of whole colons stained with methylene blue. B normal epithelium with normal crypts; C colonic epithelium of a rat injected with DMH showing aberrant crypts; D a focus with 1 aberrant crypt (1 AC); E a focus with 2 ACs; F a focus with 3 ACs; G a focus with 4 ACs; H a focus with ≥ 4ACs; I a magnified portion of H. ACF, aberrant crypt foci

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