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The Journal of Basic and Applied Zoology
Fig. 3 | The Journal of Basic and Applied Zoology

Fig. 3

From: Proanthocyanidin and sodium butyrate synergistically modulate rat colon carcinogenesis by scavenging free radicals and regulating the COX-2 and APC pathways

Fig. 3

A, B Calculated IHC labeling indexes (%) of Ki67 (A) and caspase-3 (B); *significance vs. G1 at P < 0.05; **significance versus G2 and G3 at P < 0.05 (ANOVA); samples from 10 rats/group were subjected to IHC analysis. C–G Photomicrographs of hematoxylin and eosin-stained rat colonic epithelia; C DMH-administered control (G1); D DMH + NaB-treated rats (G2); E DMH + GSPE-treated rats (G3); F DMH + NaB + GSPE-treated rats (G4); G normal control (G5). 10 rats/group were subjected to hematoxylin and eosin staining. H–L IHC staining photomicrographs of Ki67. H DMH-injected rats; I DMH + NaB-treated rats; J DMH + GSPE-treated rats; K DMH + NaB + GSPE-treated rats; L normal control. M–Q IHC staining photomicrographs of caspase-3. M DMH-injected rats; N DMH + NaB-treated rats; O DMH + GSPE-treated rats; P DMH + NaB + GSPE-treated rats; Q normal control. IHC, immunohistochemistry

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